OMR(Order-made Medical Research) succeeded in manufacturing membrane protein antibodies, which was difficult with existing technology, and dramatically expanded the number of target molecules for antibody medicines. By applying and developing this, it has become possible to challenge the field of truly groundbreaking antibody medicines that target intracellular molecules, disease specific immunogenicity changes, which were difficult to target antibodies.
Production of target antibody by
OMR-WHONIZ Antibody Platform
Challenge in the field of antibody medicine
Based on the “National Antibody Cluster” in Hongcheon, Korea, together with Wide River Institute of Immunology, Seoul National University, WHONIZ and OMR are focusing on the industrialization of antibody medicines by producing customized antibodies that target not only viral diseases but also intracellular molecules and specific antigenic changes that were difficult to target with antibodies, and disease treatments so that we can contribute to the ‘Universal Human Health Improvement’.
Polyclonal antibody
Project (Tentative) | Disease | Antibody type | Product | Remark |
IYPOLY PLUS | SARS-CoV-2 | IgY (Polyclonal) | Nasal Spray | Preventive agents |
IYPOLY +A | ADE caused by SARS-CoV-2 | IgY (Polyclonal) | Nasal Spray | Preventive agents |
IYPOLY +M | Monkeypox | IgY (Polyclonal) | Nasal Spray | Preventive agents |
IYPOLY +R | Human Rota virus | IgY (Polyclonal) | Nasal Spray, Etc. | Preventive agents, Therapeutics |
Monoclonal antibody
Indication | Target | Antibody type | Remark |
Therapeutic Antibodies for the Treatment of Cancer |
VEGF (Gastrointestinal Cancer) VEGF (Lung Cancer) VEGF (Other Cancers) VEGF (Ophthalmic Parts) CD20 (Lymphoma) CD20 (Leukemia) CD20 (Other Disease) C001 (Colorectal Cancer) |
Monoclonal | Medicine |
Autoimmune diseases | A002 (Autoimmune diseases) | Monoclonal | Medicine |
SARS-CoV-2 | I003 (SARS-CoV-2) | Monoclonal | Therapeutics |
Status of Product Development
PRODUCT | 2020 | 2021 | 2022 | 2023 |
K-SAFE Gate&Stand | Patent Registration | Ready for product release | Stop release after the develop is complete | |
IYPOLY Nasal spray | Supply Agreement | Manufacture License Certification | Product Release |
「WHONIZ-OMR Joint Development」
Development plan for various antibody medicines using OMR antibodies
BASIC RESEARCH SEED IDEAS | 2022 | 2023 | 2024 | 2025 | 2026 | 2027 |
IYPOLY PLUS (SARS-CoV-2) |
Ready for product release | Product Release | ||||
IYPOLY +A (ADE caused by SARS-CoV-2) |
Patent Registration | Ready for product release | Product Release | |||
IYPOLY +M (Monkeypox) |
Patent Registration | Ready for product release | Product Release | |||
IYPOLY +R (Human Rota virus) |
Patent Registration | Ready for product release | Product Release | |||
Anti-colorectal cancer drug | Patent Registration | Preclinical | Clinical Stages | |||
Anti-lung cancer drug | Patent Registration | Preclinical |
Production of target antibody by
OMR-WHONIZ Antibody Platform
OMR(Order-made Medical Research) succeeded in manufacturing membrane protein antibodies, which was difficult with existing technology, and dramatically expanded the number of target molecules for antibody medicines. By applying and developing this, it has become possible to challenge the field of truly groundbreaking antibody medicines that target intracellular molecules, disease specific immunogenicity changes, which were difficult to target antibodies.
Challenge in the field of
antibody medicine
Based on the “National Antibody Cluster” in Hongcheon, Korea, together with Wide River Institute of Immunology, Seoul National University, WHONIZ and OMR are focusing on the industrialization of antibody medicines by producing customized antibodies that target not only viral diseases but also intracellular molecules and specific antigenic changes that were difficult to target with antibodies, and disease treatments so that we can contribute to the ‘Universal Human Health Improvement’.
【WHONIZ-OMR】
ANTIBODY PLATFORM
Polyclonal antibody
Project (Tentative) | Disease | Antibody type | Product | Remark |
IYPOLY PLUS | SARS-CoV-2 | IgY (Polyclonal) | Nasal Spray | Preventive agents |
IYPOLY +A | ADE caused by SARS-CoV-2 | IgY (Polyclonal) | Nasal Spray | Preventive agents |
IYPOLY +M | Monkeypox | IgY (Polyclonal) | Nasal Spray | Preventive agents |
IYPOLY +R | Human Rota virus | IgY (Polyclonal) | Nasal Spray, Etc. | Preventive agents, Therapeutics |
Monoclonal antibody
Indication | Target | Antibody type | Remark |
Therapeutic Antibodies for the Treatment of Cancer |
VEGF (Gastrointestinal Cancer) VEGF (Lung Cancer) VEGF (Other Cancers) VEGF (Ophthalmic Parts) CD20 (Lymphoma) CD20 (Leukemia) CD20 (Other Disease) C001 (Colorectal Cancer) |
Monoclonal | Medicine |
Autoimmune diseases | A002 (Autoimmune diseases)) | Monoclonal | Medicine |
SARS-CoV-2 | I003 (SARS-CoV-2) | Monoclonal | Therapeutics |
Status of Product Development
PRODUCT | 2020 | 2021 | 2022 | 2023 |
K-SAFE Gate&Stand | Patent Registration | Ready for product release | Stop release after the develop is complete | |
IYPOLY Nasal spray | Supply Agreement | Manufacture License Certification | Product Release |
「WHONIZ-OMR Joint Development」
Development plan for various antibody medicines using OMR antibodies
BASIC RESEARCH SEED IDEAS |
2022 | 2023 | 2024 | 2025 | 2026 | 2027 |
IYPOLY PLUS (SARS-CoV-2) |
Ready for product release |
Product Release | ||||
IYPOLY +A (ADE caused by SARS-CoV-2) |
Patent Registration |
Ready for product release |
Product Release | |||
IYPOLY +M (Monkeypox) |
Patent Registration |
Ready for product release |
Product Release | |||
IYPOLY +R (Human Rota virus) |
Patent Registration |
Ready for product release |
Product Release | |||
Anti-colorectal cancer drug |
Patent Registration |
Preclinical |
Clinical Stages |
|||
Anti-lung cancer drug |
Patent Registration |
Preclinical |