WHONIZ-OMR General Agreement secured the exclusive right to use antibody

Production of target antibody by
OMR-WHONIZ Antibody Platform

OMR(Order-made Medical Research) succeeded in manufacturing membrane protein antibodies, which was difficult with existing technology, and dramatically expanded the number of target molecules for antibody medicines. By applying and developing this, it has become possible to challenge the field of truly groundbreaking antibody medicines that target intracellular molecules, disease specific immunogenicity changes, which were difficult to target antibodies.

Challenge in the field of antibody medicine

Based on the “National Antibody Cluster” in Hongcheon, Korea, together with Wide River Institute of Immunology, Seoul National University, WHONIZ and OMR are focusing on the industrialization of antibody medicines by producing customized antibodies that target not only viral diseases but also intracellular molecules and specific antigenic changes that were difficult to target with antibodies, and disease treatments so that we can contribute to the ‘Universal Human Health Improvement’.

【WHONIZ-OMR】 ANTIBODY PLATFORM

Polyclonal antibody

Project (Tentative) Disease Antibody type Product Remark
IYPOLY PLUS SARS-CoV-2 IgY (Polyclonal) Nasal Spray Preventive agents
IYPOLY +A ADE caused by SARS-CoV-2 IgY (Polyclonal) Nasal Spray Preventive agents
IYPOLY +M Monkeypox IgY (Polyclonal) Nasal Spray Preventive agents
IYPOLY +R Human Rota virus IgY (Polyclonal) Nasal Spray, Etc. Preventive agents, Therapeutics

Monoclonal antibody

Indication Target Antibody type Remark
Therapeutic Antibodies for
the Treatment of Cancer
VEGF (Gastrointestinal Cancer)
VEGF (Lung Cancer)
VEGF (Other Cancers)
VEGF (Ophthalmic Parts)
CD20 (Lymphoma)
CD20 (Leukemia)
CD20 (Other Disease)
C001 (Colorectal Cancer)
Monoclonal Medicine
Autoimmune diseases A002 (Autoimmune diseases) Monoclonal Medicine
SARS-CoV-2 I003 (SARS-CoV-2) Monoclonal Therapeutics
Product Pipeline

Status of Product Development

PRODUCT 2020 2021 2022 2023
K-SAFE Gate&Stand Patent Registration Ready for product release Stop release after the develop is complete
IYPOLY Nasal spray Supply Agreement Manufacture License Certification Product Release

「WHONIZ-OMR Joint Development」

Development plan for various antibody medicines using OMR antibodies

BASIC RESEARCH SEED IDEAS 2022 2023 2024 2025 2026 2027
IYPOLY PLUS
(SARS-CoV-2)
Ready for product release Product Release
IYPOLY +A
(ADE caused by SARS-CoV-2)
Patent Registration Ready for product release Product Release
IYPOLY +M
(Monkeypox)
Patent Registration Ready for product release Product Release
IYPOLY +R
(Human Rota virus)
Patent Registration Ready for product release Product Release
Anti-colorectal cancer drug Patent Registration Preclinical Clinical Stages
Anti-lung cancer drug Patent Registration Preclinical
WHONIZ-OMR General Agreement secured the exclusive right to use antibody
Production of target antibody by
OMR-WHONIZ Antibody Platform

OMR(Order-made Medical Research) succeeded in manufacturing membrane protein antibodies, which was difficult with existing technology, and dramatically expanded the number of target molecules for antibody medicines. By applying and developing this, it has become possible to challenge the field of truly groundbreaking antibody medicines that target intracellular molecules, disease specific immunogenicity changes, which were difficult to target antibodies.

Challenge in the field of
antibody medicine

Based on the “National Antibody Cluster” in Hongcheon, Korea, together with Wide River Institute of Immunology, Seoul National University, WHONIZ and OMR are focusing on the industrialization of antibody medicines by producing customized antibodies that target not only viral diseases but also intracellular molecules and specific antigenic changes that were difficult to target with antibodies, and disease treatments so that we can contribute to the ‘Universal Human Health Improvement’.

【WHONIZ-OMR】
ANTIBODY PLATFORM

Polyclonal antibody

Project (Tentative) Disease Antibody type Product Remark
IYPOLY PLUS SARS-CoV-2 IgY (Polyclonal) Nasal Spray Preventive agents
IYPOLY +A ADE caused by SARS-CoV-2 IgY (Polyclonal) Nasal Spray Preventive agents
IYPOLY +M Monkeypox IgY (Polyclonal) Nasal Spray Preventive agents
IYPOLY +R Human Rota virus IgY (Polyclonal) Nasal Spray, Etc. Preventive agents, Therapeutics

Monoclonal antibody

Indication Target Antibody type Remark
Therapeutic Antibodies for the Treatment of Cancer VEGF (Gastrointestinal Cancer)
VEGF (Lung Cancer)
VEGF (Other Cancers)
VEGF (Ophthalmic Parts)
CD20 (Lymphoma)
CD20 (Leukemia)
CD20 (Other Disease)
C001 (Colorectal Cancer)
Monoclonal Medicine
Autoimmune diseases A002 (Autoimmune diseases)) Monoclonal Medicine
SARS-CoV-2 I003 (SARS-CoV-2) Monoclonal Therapeutics
Product Pipeline

Status of Product Development

PRODUCT 2020 2021 2022 2023
K-SAFE Gate&Stand Patent Registration Ready for product release Stop release after the develop is complete
IYPOLY Nasal spray Supply Agreement Manufacture License Certification Product Release

「WHONIZ-OMR Joint Development」

Development plan for various antibody medicines using OMR antibodies

BASIC
RESEARCH
SEED IDEAS
2022 2023 2024 2025 2026 2027
IYPOLY PLUS
(SARS-CoV-2)
Ready for
product release
Product Release
IYPOLY +A
(ADE caused by
SARS-CoV-2)
Patent
Registration
Ready for
product release
Product Release
IYPOLY +M
(Monkeypox)
Patent
Registration
Ready for
product release
Product Release
IYPOLY +R
(Human Rota
virus)
Patent
Registration
Ready for
product release
Product Release
Anti-colorectal
cancer drug
Patent
Registration
Preclinical Clinical
Stages
Anti-lung
cancer drug
Patent
Registration
Preclinical